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Browse our Isle of Palms luxury vacation rentals - a group of homes that really stand out from the rest. Why settle for anything less while vacationing on the Isle of Palms? These properties are truly some of the most incredible properties in all of Charleston, located on the gorgeous Isle of Palms. Our luxury homes feature premier ocean views, top-of-the-line furnishings, high-end amenities, and resort-style pools. Browse below to see a few prime examples of our Isle of Palms luxury vacation rentals, and reserve your perfect home. Our best properties book up quickly, so make sure to book ahead of time for the best selection. Or visit our main search page to view all of our Isle of Palms vacation rentals. We look forward to seeing you on the IOP!